European Guidelines for Lynch Syndrome

The 2013 European Guidelines for Lynch Syndrome management have been superseded by the recently published UK gene-specific guidelines.  The full original text for the 2013 guidelines produced by the Mallorca group can be accessed here.

National and International Guidelines

Peer-reviewed published guidelines from national and international expert groups are available at the links here below. For additional UKCGG guidelines and leaflets, please click here. 

Familial breast cancer: classification, care and managing breast cancer and related risks in people with a family history of breast cancer

The 2013 NICE guidelines for familial breast cancer are available here.

Guidelines for the management of hereditary colorectal cancer from the BSG /ACPGBI/UKCGG

UKCGG has worked with the British Society of Gastroenterology and the Association of Coloproctologists of Great Britain and Ireland to produce new guidance on the screening and management of patients with an increased genetic predisposition to colorectal cancer. 

Unfortunately there is not enough evidence to review regarding the use of aspirin in patients at high risk of colorectal cancer outside of the context of Lynch Syndrome. However, given the evidence supporting use of aspirin in Lynch Syndrome and the growing body of evidence with respect to reduction in colorectal cancer risk with aspirin in the general population, we advise that patients at high risk of developing colorectal cancer on the basis of their family history should see their GP to discuss the risks and benefits of low dose (75-150mg) daily aspirin for bowel cancer risk reduction.